Harvard Medical School landmark report
As is well known, the redefinition of death as “brain death” was prompted by advances in life-sustaining technology and related challenges in obtaining organs for transplantation. These issues were placed center stage in the 1968 Harvard Medical School landmark report that proposed “to define irreversible coma as a new criterion of death” (Beecher et al. 1968, 337). What marked the end of life was irreversible brain damage, a state of the body in which the patient’s heart continued to beat but he or she had suffered “permanent loss of intellect” (337).
You can see the original publishing at this SlideShare link: